John S. Robertson directed this 1920 version of Robert Louis Stevenson's famed book. John Barrymore's performance as Mr. Hyde received many plaudits on the release of this adaption and the film was an acknowledged success.

Dr. Jekyll (John Barrymore) is a London doctor, progressive in his medical research, conservative and repressed in his personal life. A friend encourages him to explore the underside of life with a visit to a London music hall. Dancer Nita Naldi arouses Jekyll's repressed sensibilities, and when she embraces him, the doctor runs off. Later, Jekyll speculates on the advantage of separating the two natures of man in different bodies- one could "yield to every evil impulse, yet leave the soul untouched." Jekyll's scientific passion leads him to a formula that brings out his other side, Mr. Hyde, a man without a conscience.